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- $Unique_ID{BRK03695}
- $Pretitle{}
- $Title{Edema, Idiopathic}
- $Subject{Edema, Idiopathic Cyclic Edema Distress Edema Periodic Edema Periodic
- Swelling Stress Edema Angioedema Chronic Interstitial Nephritis}
- $Volume{}
- $Log{}
-
- Copyright (C) 1989 National Organization for Rare Disorders, Inc.
-
- 634:
- Edema, Idiopathic
-
- ** IMPORTANT **
- It is possible that the main title of this article (Idiopathic Edema) is
- not the name you expected. Please check the SYNONYM list to find the
- alternate names and disorder subdivisions covered by this article.
-
- Synonyms
-
- Cyclic Edema
- Distress Edema
- Periodic Edema
- Periodic Swelling
- Stress Edema
-
- Information on the following disorders can be found in the Related
- Disorders section of this report:
-
- Angioedema
- Chronic Interstitial Nephritis
-
- General Discussion
-
- ** REMINDER **
- The information contained in the Rare Disease Database is provided for
- educational purposes only. It should not be used for diagnostic or treatment
- purposes. If you wish to obtain more information about this disorder, please
- contact your physician and/or the agencies listed in the "Resources" section
- of this report.
-
- Idiopathic Edema is a common disorder that occurs almost exclusively in
- women. It is characterized by salt retention in the absence of heart,
- kidney, or liver disease. The swelling (edema) may be episodic or
- persistent. Swelling of the face, hands, and feet develops rapidly,
- frequently accompanied by headache, irritability, and depression. Weight
- gain also occurs.
-
- Symptoms
-
- Idiopathic Edema is characterized by swelling (edema) that may occur
- occasionally or chronically. It seems to affect women almost exclusively.
- The swelling develops rapidly and usually affects the face, hands, and feet.
- The abdomen may also be bloated. Fatigue, irritability, depression, tension,
- and headache usually also occur. The course of the disorder is often related
- to the menstrual cycle. Some patients can gain as much as 10 to 12 lbs.
- during a 24-hour period, accompanied by a decrease in urine output. Patients
- seem to have an exaggerated response to standing for long periods of time,
- resulting in significant pitting edema of their lower extremities.
-
- Causes
-
- The exact cause of Idiopathic Edema is not known. The disorder may be caused
- by an imbalance of hormones such as estrogens and progesterone. The
- aldosterone response to upright posture plays a role in sodium and water
- retention in people with this disorder.
-
- Affected Population
-
- Idiopathic Edema affects young to middle-aged females almost exclusively.
-
- Related Disorders
-
- Angioedema is a widespread swelling of tissue under the skin. It occurs as
- an allergic reaction following either the injection of certain drugs, or
- insect stings or bites. Eating certain foods to which the individual is
- allergic, such as eggs, shellfish, nuts, or fruit, may cause a similar
- reaction. The swelling usually affects the back of the hands and feet, the
- eyelids, lips, genital area, and mucous membranes. Swelling of the trachea
- and bronchial passages may produce breathing difficulty. (For more
- information, use "Angioedema" as your search term in the Rare Disease
- Database.)
-
- Chronic Interstitial Nephritis is a kidney disorder usually caused by
- prolonged consumption of pain medications (e.g., phenacetin). It is
- characterized by breathing difficulty, headache, indigestion (dyspepsia),
- diarrhea and passage of large quantities of light-colored urine.
-
- Therapies: Standard
-
- When Idiopathic Edema persists, carefully measured use of the drugs captopril
- or spironolactone may restore the proper aldosterone response to the upright
- posture, and thus reverse the edema.
-
- Therapies: Investigational
-
- This disease entry is based upon medical information available through April
- 1989. Since NORD's resources are limited, it is not possible to keep every
- entry in the Rare Disease Database completely current and accurate. Please
- check with the agencies listed in the Resources section for the most current
- information about this disorder.
-
- Resources
-
- For more information on Idiopathic Edema, please contact:
-
- National Organization for Rare Disorders (NORD)
- P.O. Box 8923
- New Fairfield, CT 06812-1783
- (203) 746-6518
-
- National Digestive Diseases Information Clearinghouse
- Box NDDIC
- Bethesda, MD 20892
- (301) 468-6344
-
- References
-
- LONG-TERM FUROSEMIDE TREATMENT IN IDIOPATHIC EDEMA: M. Shichiri, et al.;
- Arch Intern Med (November 1984: issue 144(11)). Pp. 2161-2164.
-
- IDIOPATHIC EDEMA IN A MALE: I. Weinberger, et al.; American Journal Med
- Sci (July-August 1984: issue 288(1)). Pp. 27-31.
-
- THERAPEUTIC RESPONSE OF IDIOPATHIC EDEMA TO CAPTOPRIL: D. Docci, et al.;
- Nephron (1983: issue 34(3)). Pp. 198-200.
-
-